25-50 mg q2 weeks dosing is for which antipsychotic formulation?

25-50 mg q2 weeks dosing is for which antipsychotic formulation?

• A. Risperidone RBP-7000 (Perseris)
• B. Paliperidone palmitate 1-monthly
• C. Aripiprazole Maintena
• D. Risperidone (Risperdal Consta)

Answer: (D)

The important idea here is the dosing interval of long-acting injectable antipsychotics. The biweekly (every two weeks) schedule is specific to Risperidone long-acting injectable (Risperdal Consta), which is given by intramuscular injection every two weeks and comes in 25 mg to 50 mg per injection as part of maintaining steady drug levels. In contrast, the other formulations shown are monthly injections (every 4 weeks), including paliperidone palmitate (Invega Sustenna), aripiprazole (Maintena), and the subcutaneous Risperidone Perseris. So a dosing regimen of 25-50 mg every two weeks aligns with Risperdal Consta, not the monthly formulations.

The important idea here is the dosing interval of long-acting injectable antipsychotics. The biweekly (every two weeks) schedule is specific to Risperidone long-acting injectable (Risperdal Consta), which is given by intramuscular injection every two weeks and comes in 25 mg to 50 mg per injection as part of maintaining steady drug levels. In contrast, the other formulations shown are monthly injections (every 4 weeks), including paliperidone palmitate (Invega Sustenna), aripiprazole (Maintena), and the subcutaneous Risperidone Perseris. So a dosing regimen of 25-50 mg every two weeks aligns with Risperdal Consta, not the monthly formulations.