According to the equivalence data, olanzapine 1 mg is equivalent to 40 mg, and Risperdal 1 mg is equivalent to 150 mg.

According to the equivalence data, olanzapine 1 mg is equivalent to 40 mg, and Risperdal 1 mg is equivalent to 150 mg.

• A. Olanzapine 1 mg = 40 mg; Risperdal 1 mg = 150 mg
• B. Olanzapine 1 mg = 20 mg; Risperdal 1 mg = 100 mg
• C. Olanzapine 1 mg = 60 mg; Risperdal 1 mg = 200 mg
• D. Olanzapine 1 mg = 80 mg; Risperdal 1 mg = 180 mg

Answer: (A)

Dose equivalence data let you compare potencies of antipsychotics on a common scale, usually to a reference like chlorpromazine. Here, the data say that one milligram of olanzapine is equivalent to forty milligrams of the reference, and one milligram of Risperdal is equivalent to one hundred fifty milligrams of the reference. That means the statement “olanzapine 1 mg = 40 mg; Risperdal 1 mg = 150 mg” matches those figures exactly. It also shows that risperidone is more potent per milligram than olanzapine on this equivalence scale. The other options propose numbers that do not align with the given equivalence data, so they’re not correct.

Dose equivalence data let you compare potencies of antipsychotics on a common scale, usually to a reference like chlorpromazine. Here, the data say that one milligram of olanzapine is equivalent to forty milligrams of the reference, and one milligram of Risperdal is equivalent to one hundred fifty milligrams of the reference. That means the statement “olanzapine 1 mg = 40 mg; Risperdal 1 mg = 150 mg” matches those figures exactly. It also shows that risperidone is more potent per milligram than olanzapine on this equivalence scale. The other options propose numbers that do not align with the given equivalence data, so they’re not correct.