Asenapine, olanzapine, quetiapine, risperidone

Asenapine, olanzapine, quetiapine, risperidone

• A. Quetiapine, olanzapine, risperidone, ziprasidone
• B. Acute adjunctive therapy for bipolar disorder
• C. Dementia treatment for Alzheimer-type
• D. Postpartum psychosis treatment

Answer: (B)

These drugs are atypical antipsychotics, and used in bipolar disorder they’re typically added to a mood stabilizer for acute mania or mixed episodes. When mania isn’t fully controlled by lithium or valproate alone, adding one of these antipsychotics can quickly reduce agitation, pressured speech, grandiosity, and psychotic symptoms, speeding recovery in the acute phase. That combination—an antipsychotic added to mood stabilization for acute bipolar episodes—best fits the concept being tested. They’re not standard treatments for Alzheimer’s dementia, where antipsychotics have limited indication and safety concerns, nor is the focus on postpartum psychosis in this context.

These drugs are atypical antipsychotics, and used in bipolar disorder they’re typically added to a mood stabilizer for acute mania or mixed episodes. When mania isn’t fully controlled by lithium or valproate alone, adding one of these antipsychotics can quickly reduce agitation, pressured speech, grandiosity, and psychotic symptoms, speeding recovery in the acute phase. That combination—an antipsychotic added to mood stabilization for acute bipolar episodes—best fits the concept being tested. They’re not standard treatments for Alzheimer’s dementia, where antipsychotics have limited indication and safety concerns, nor is the focus on postpartum psychosis in this context.