What is the monograph dose for Brexpiprazole for psychosis?

What is the monograph dose for Brexpiprazole for psychosis?

• A. 1-2 mg once daily
• B. 3-5 mg once daily
• C. 2-4 mg once daily
• D. 4-6 mg once daily

Answer: (C)

Brexpiprazole used for psychosis is given in a daily dose that sits within a specific therapeutic window. The monograph sets the target range at 2–4 mg once daily, with starting treatment often at 1 mg and then titrating up to 2–4 mg. The reason this range is preferred is that it tends to provide symptom control while keeping side effects at a manageable level; doses higher than 4 mg/day don’t substantially improve efficacy and increase the risk of adverse effects like akathisia and metabolic changes. So, the recommended daily dose for schizophrenia falls within 2–4 mg.

Brexpiprazole used for psychosis is given in a daily dose that sits within a specific therapeutic window. The monograph sets the target range at 2–4 mg once daily, with starting treatment often at 1 mg and then titrating up to 2–4 mg. The reason this range is preferred is that it tends to provide symptom control while keeping side effects at a manageable level; doses higher than 4 mg/day don’t substantially improve efficacy and increase the risk of adverse effects like akathisia and metabolic changes. So, the recommended daily dose for schizophrenia falls within 2–4 mg.