What is the prevalence of antidiuretic hormone dysfunction in individuals with schizophrenia?

What is the prevalence of antidiuretic hormone dysfunction in individuals with schizophrenia?

• A. 1-2%
• B. 30-40%
• C. 6-20%
• D. 50-60%

Answer: (C)

ADH dysfunction in schizophrenia reflects disruptions in how the body handles water balance, which can show up as hyponatremia or other water balance abnormalities. Across studies, the prevalence is not rare but also not ubiquitous, with estimates typically clustering in the low-to-mid teens. The best-supported range is about 6-20%, which matches the variability seen in different samples and diagnostic methods. That makes this option the most consistent with the literature. Very low rates (1-2%) underestimate how often water balance issues appear, while very high rates (30-60%) exceed what most studies find.

ADH dysfunction in schizophrenia reflects disruptions in how the body handles water balance, which can show up as hyponatremia or other water balance abnormalities. Across studies, the prevalence is not rare but also not ubiquitous, with estimates typically clustering in the low-to-mid teens. The best-supported range is about 6-20%, which matches the variability seen in different samples and diagnostic methods. That makes this option the most consistent with the literature. Very low rates (1-2%) underestimate how often water balance issues appear, while very high rates (30-60%) exceed what most studies find.