Which drug is listed for nausea and vomiting medications?

Which drug is listed for nausea and vomiting medications?

• A. Chlorpromazine
• B. Trifluoperazine
• C. Haloperidol
• D. Perphenazine

Answer: (A)

Dopamine blockade in the chemoreceptor trigger zone explains why some antipsychotics also work as antiemetics. Chlorpromazine, a low-potency phenothiazine, has strong antiemetic activity because it antagonizes D2 receptors in the CTZ, which helps suppress vomiting and nausea. This makes it a drug often listed for nausea and vomiting in addition to its antipsychotic use. The other options are higher-potency typical antipsychotics, whose primary roles are treating psychosis rather than serving as antiemetics. While they can have antiemetic effects, they are not as commonly listed for nausea and vomiting due to greater risk of extrapyramidal symptoms and other side effects. Hence chlorpromazine is the most appropriate choice for a medication listed for nausea and vomiting.

Dopamine blockade in the chemoreceptor trigger zone explains why some antipsychotics also work as antiemetics. Chlorpromazine, a low-potency phenothiazine, has strong antiemetic activity because it antagonizes D2 receptors in the CTZ, which helps suppress vomiting and nausea. This makes it a drug often listed for nausea and vomiting in addition to its antipsychotic use.

The other options are higher-potency typical antipsychotics, whose primary roles are treating psychosis rather than serving as antiemetics. While they can have antiemetic effects, they are not as commonly listed for nausea and vomiting due to greater risk of extrapyramidal symptoms and other side effects. Hence chlorpromazine is the most appropriate choice for a medication listed for nausea and vomiting.