Which drug is used for nausea and vomiting medications?

Which drug is used for nausea and vomiting medications?

• A. Chlorpromazine
• B. Trifluoperazine
• C. Haloperidol
• D. Perphenazine

Answer: (A)

Chlorpromazine works as an antiemetic because it blocks dopamine D2 receptors in the chemoreceptor trigger zone (CTZ) of the brain. The CTZ detects circulating toxins and signals the vomiting center to induce nausea and vomiting. By antagonizing D2 receptors in this area, chlorpromazine interrupts that signal and reduces the vomiting reflex, making it a classic and effective antiemetic, commonly used for nausea associated with anesthesia or chemotherapy. The other drugs listed are antipsychotics with antiemetic effects due to D2 blockade as well, but they are not as traditionally or primarily used as antiemetics. Chlorpromazine’s established role as a nausea-and-vomiting agent is why it’s the expected choice.

Chlorpromazine works as an antiemetic because it blocks dopamine D2 receptors in the chemoreceptor trigger zone (CTZ) of the brain. The CTZ detects circulating toxins and signals the vomiting center to induce nausea and vomiting. By antagonizing D2 receptors in this area, chlorpromazine interrupts that signal and reduces the vomiting reflex, making it a classic and effective antiemetic, commonly used for nausea associated with anesthesia or chemotherapy.

The other drugs listed are antipsychotics with antiemetic effects due to D2 blockade as well, but they are not as traditionally or primarily used as antiemetics. Chlorpromazine’s established role as a nausea-and-vomiting agent is why it’s the expected choice.