Which medication is used for drug-induced psychosis?

Which medication is used for drug-induced psychosis?

• A. Risperidone
• B. Clozapine
• C. Paliperidone
• D. Olanzapine

Answer: (A)

Treating drug-induced psychosis involves using an antipsychotic to quickly control positive symptoms like delusions and hallucinations while monitoring for withdrawal and toxicity. Risperidone is a well-established choice because it effectively reduces these psychotic symptoms through dopamine D2 receptor blockade, with additional 5-HT2A antagonism that can help with mood and agitation. This balance supports rapid symptom control in acute, substance-related psychosis and is widely used in clinical practice. Clozapine is typically reserved for treatment-resistant cases due to its serious side effects, including agranulocytosis. Olanzapine can be effective but carries notable metabolic risks and sedation, which may be less desirable in acute intoxication settings. Paliperidone is similar to risperidone but is often considered after trying risperidone or in specific contexts.

Treating drug-induced psychosis involves using an antipsychotic to quickly control positive symptoms like delusions and hallucinations while monitoring for withdrawal and toxicity. Risperidone is a well-established choice because it effectively reduces these psychotic symptoms through dopamine D2 receptor blockade, with additional 5-HT2A antagonism that can help with mood and agitation. This balance supports rapid symptom control in acute, substance-related psychosis and is widely used in clinical practice.

Clozapine is typically reserved for treatment-resistant cases due to its serious side effects, including agranulocytosis. Olanzapine can be effective but carries notable metabolic risks and sedation, which may be less desirable in acute intoxication settings. Paliperidone is similar to risperidone but is often considered after trying risperidone or in specific contexts.