Which Paliperidone palmitate formulation is dosed every 4 weeks with a dose of 117 mg (75 mg paliperidone) IM?

Which Paliperidone palmitate formulation is dosed every 4 weeks with a dose of 117 mg (75 mg paliperidone) IM?

• A. Paliperidone palmitate 1-monthly
• B. Paliperidone palmitate 3-monthly
• C. Paliperidone palmitate 6-monthly
• D. Risperidone (Risperdal Consta)

Answer: (A)

The key idea is the dosing schedule for Paliperidone palmitate’s long-acting injectable forms. The formulation given every 4 weeks at 117 mg (which equals 75 mg of paliperidone) is the 1-monthly option. This monthly schedule is specifically designed for ongoing, monthly administration after any loading doses. The other paliperidone palmitate options are for longer intervals (every 3 months or every 6 months) and use different total doses, so they don’t match the 4-weekly 117 mg regimen. Risperidone (Risperdal Consta) is a separate long-acting injectable with its own dosing schedule and is not paliperidone palmitate.

The key idea is the dosing schedule for Paliperidone palmitate’s long-acting injectable forms. The formulation given every 4 weeks at 117 mg (which equals 75 mg of paliperidone) is the 1-monthly option. This monthly schedule is specifically designed for ongoing, monthly administration after any loading doses. The other paliperidone palmitate options are for longer intervals (every 3 months or every 6 months) and use different total doses, so they don’t match the 4-weekly 117 mg regimen. Risperidone (Risperdal Consta) is a separate long-acting injectable with its own dosing schedule and is not paliperidone palmitate.